Description

4-Bromo-2-Chloro-6-Fluoroanisole is a high-purity halogenated anisole derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique substitution pattern, which provides versatile reactivity for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where its halogenated structure contributes to biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with specific electronic or optical properties.
• Organic Electronics: Investigated as a precursor for small-molecule semiconductors and charge-transport materials in OLED and OPV applications.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling rapid diversification of chemical space.
• Chemical Biology Probes: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	4-Bromo-2-Chloro-6-Fluoroanisole
CAS No.	261762-34-9
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	1-Bromo-3-chloro-5-fluoro-2-methoxybenzene; 2-Chloro-6-fluoro-4-bromoanisole; 4-Bromo-2-chloro-6-fluoromethoxybenzene; Anisole, 4-bromo-2-chloro-6-fluoro-; Benzene, 1-bromo-3-chloro-5-fluoro-2-methoxy-; 2-Methoxy-5-bromo-3-chloro-1-fluorobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-6-Fluoroanisole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and specific tests is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.