Description

Cyclohexanecarboxylic Acid, 1-Amino-2-Methyl-, (1R,2S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its rigid cyclohexane backbone and functional groups, which are critical for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients where stereochemistry is a key determinant of biological activity. CAS No. 261355-46-8.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring stereoselective action.
• Agrochemical Synthesis: Used in the design and production of advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical & Specialty Material Production: Employed in the synthesis of complex fragrances, flavors, and advanced materials where specific stereochemistry imparts desired properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 1-Amino-2-Methyl-, (1R,2S)- (9Ci)
CAS No.	261355-46-8
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(1R,2S)-1-Amino-2-methylcyclohexanecarboxylic acid; (1R,2S)-1-Amino-2-methyl-1-cyclohexanecarboxylic acid; trans-1-Amino-2-methylcyclohexanecarboxylic acid (specific to (1R,2S)); 1-Amino-2-methylcyclohexanecarboxylic acid, (1R,2S)-rel-; 2-Methyl-1-aminocyclohexanecarboxylic acid; A building block for constrained β-amino acids
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanecarboxylic Acid, 1-Amino-2-Methyl-, (1R,2S)- (9Ci) is produced and tested under a strict quality management system. We employ advanced analytical techniques, including chiral HPLC, NMR, and mass spectrometry, to ensure excellent enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.