Description

2,4-Difluoro-1-propoxybenzene is a high-purity fluorinated aromatic ether building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both alkoxy and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and thermal stability.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing their chemical resistance, surface properties, and durability.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl and other complex aromatic systems.
• Chemical Research: A valuable reagent in academic and industrial research laboratories for exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	2,4-Difluoro-1-propoxybenzene
CAS No.	259655-00-0
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	1-Propoxy-2,4-difluorobenzene; Benzene, 2,4-difluoro-1-propoxy-; 2,4-Difluorophenyl propyl ether; Propyl 2,4-difluorophenyl ether; 2,4-Difluorophenoxypropane
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-1-propoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.