Description

Cryodesiccant Human Fibrinogen is a high-purity, lyophilized form of the essential blood plasma glycoprotein. This product is critical for its role in the final stages of the blood coagulation cascade, forming the structural matrix of a stable clot. It is primarily utilized in advanced biomedical research, diagnostic assay development, and as a key starting material in the production of surgical hemostats and tissue sealants. The material is processed under stringent conditions to preserve its biological activity and structural integrity.

Application

• Biomedical Research & Development: Used as a standard or substrate in studies of hemostasis, thrombosis, wound healing, and angiogenesis.
• Diagnostic Manufacturing: Serves as a critical raw material in the production of coagulation factor assay kits and other in-vitro diagnostic (IVD) reagents.
• Tissue Engineering: Acts as a biological scaffold or matrix component for cell culture and the development of engineered tissues.
• Hemostatic Agent Production: A primary ingredient in the formulation of fibrin sealants, glues, and topical hemostatic products used in surgical settings.
• Cell Culture & Biochemistry: Employed as a coating agent to promote cell adhesion and growth in various cell-based assays and production systems.
• Reference Standard: Functions as a calibration standard in quality control laboratories for potency testing of fibrinogen-based therapeutics.

Basic Information

Product Name	Cryodesiccant Human Fibrinogen
CAS No.	259242-63-2
Molecular Formula	Contact for details
Molecular Weight	~340,000 Da (multimeric complex)
Synonyms	Human Fibrinogen, Lyophilized
Factor I
Fibrinogen, Human
Lyophilized Human Fibrinogen
Fibrinogen Concentrate (Human)
Coagulation Factor I
Fibrinogen, Cryodesiccated
EINECS	Contact for details

Quality Control

Our Cryodesiccant Human Fibrinogen is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for purity, biological activity (clottability), and consistency. Quality parameters are assessed using methods including SDS-PAGE, HPLC, and functional clotting assays. A comprehensive Certificate of Analysis (COA) documenting identity, purity, potency, and safety tests (e.g., sterility, endotoxin) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -20°C or below. This product is hygroscopic (moisture-sensitive) and easily oxidized; the original vial should be kept sealed under inert atmosphere and allowed to equilibrate to room temperature before opening to prevent condensation. For long-term stability, avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or solid
Identification (Immunological)	Complies
Purity (SDS-PAGE)	> 95% (Non-reduced)
Clottable Protein	> 90% of total protein
Solubility	Clear, slightly opalescent solution in specified buffer
pH (in solution)	6.5 - 7.5
Moisture (Karl Fischer)	< 3.0 %
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.