Description

[1-(2-Amino-Ethyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity, protected amine derivative used as a critical building block in advanced organic synthesis. Its value lies in providing a versatile piperidine-ethylamine scaffold with orthogonal protecting groups, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and receptor-targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides.
• Peptidomimetics & Drug Discovery: Serves as a crucial scaffold in medicinal chemistry for creating peptide mimics and screening compound libraries.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for metal complexes and asymmetric catalysts.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a functionalized piperidine core.

Basic Information

Product Name	[1-(2-Amino-Ethyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	259180-79-5
Molecular Formula	C12H25N3O2
Molecular Weight	243.35 g/mol
Synonyms	tert-Butyl N-[1-(2-aminoethyl)piperidin-4-yl]carbamate; 4-[(tert-Butoxycarbonyl)amino]-1-(2-aminoethyl)piperidine; 1-(2-Aminoethyl)-4-[(tert-butoxycarbonyl)amino]piperidine; N-Boc-4-amino-1-(2-aminoethyl)piperidine; 1-(2-Aminoethyl)piperidin-4-amine, N-Boc derivative; BOC-Pip-NH-CH2-CH2-NH2; (4-Amino-1-(2-aminoethyl)piperidin-1-yl)(tert-butoxy)methanone
EINECS	Contact for details

Quality Control

Our [1-(2-Amino-Ethyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.