Description

Acetamide, n-(3-Fluoro-2-Thienyl)- (9Ci) is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the unique thiophene and fluorine motifs are leveraged to modulate biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific molecular frameworks into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorothiophene moiety can enhance bioavailability and environmental stability.
• Material Science Precursor: Acts as a building block for the synthesis of advanced organic electronic materials, such as semiconductors and conductive polymers, due to the electron-rich thiophene ring.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs), facilitating novel chemical transformations.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on understanding the effects of fluorine substitution on heterocyclic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies engaged in custom synthesis projects for clients requiring specific, high-purity fluorinated intermediates.

Basic Information

Product Name	Acetamide, n-(3-Fluoro-2-Thienyl)- (9Ci)
CAS No.	258522-54-2
Molecular Formula	C6H6FNOS
Molecular Weight	159.18 g/mol
Synonyms	N-(3-Fluoro-2-thienyl)acetamide; N-(3-Fluorothiophen-2-yl)acetamide; 3-Fluoro-2-acetamidothiophene; Acetamide, N-(3-fluoro-2-thienyl)-; 2-Acetamido-3-fluorothiophene; 258522-54-2; N-Acetyl-3-fluoro-2-aminothiophene
EINECS	Contact for details

Quality Control

Our Acetamide, n-(3-Fluoro-2-Thienyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to consistent quality and traceability supports your research and development needs from discovery through to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.