Description

Hynic-Toc Trifluoroacetate is a bifunctional chelating agent designed for the efficient radiolabeling of biomolecules with technetium-99m for diagnostic imaging. This compound is critical for researchers and radiochemists developing targeted radiopharmaceuticals, as it enables stable conjugation to peptides, antibodies, or other targeting vectors. It is primarily used in the fields of nuclear medicine, molecular imaging, and preclinical research to create novel diagnostic probes.

Application

• Conjugation and radiolabeling of peptides for SPECT (Single-Photon Emission Computed Tomography) imaging agents.
• Development of technetium-99m labeled monoclonal antibodies for tumor targeting and diagnosis.
• Preparation of receptor-targeted radiopharmaceuticals for cardiovascular and neurological imaging.
• Research and development of novel bifunctional chelators in academic and industrial laboratories.
• Production of kit-formulated precursors for convenient 99mTc labeling in clinical settings.
• Molecular imaging probe development for preclinical cancer research and drug discovery.

Basic Information

Product Name	Hynic-Toc Trifluoroacetate
CAS No.	257943-19-4
Molecular Formula	C33H45F3N6O7
Molecular Weight	694.75 g/mol
Synonyms	6-Hydrazinonicotinyl-Toc; HYNIC-TOC; HYNIC-TOC TFA; 6-Hydrazinopyridine-3-carboxylic acid - [Tyr3]-Octreotide conjugate trifluoroacetate; Somatostatin analog HYNIC conjugate; Technetium Tc 99m HYNIC-TOC; Bifunctional Chelator-TOC conjugate
EINECS	Contact for details

Quality Control

Our Hynic-Toc Trifluoroacetate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize condensation and exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Unknown Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.