Description

Methyl 2-(3-Amino-4-Fluorophenyl)Acetate is a high-purity fluorinated aromatic ester building block, essential for the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. Its molecular structure, featuring both an amino and a fluorine substituent on the phenyl ring, makes it a versatile intermediate for introducing key pharmacophores into target molecules. This compound is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries seeking to develop new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology, central nervous system (CNS), and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic compounds used in electronic display technologies.
• Advanced Polymer Modification: Incorporated as a specialty monomer to impart specific properties like chemical resistance or altered solubility in high-performance polymers.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-value applications.

Basic Information

Product Name	Methyl 2-(3-Amino-4-Fluorophenyl)Acetate
CAS No.	257632-77-2
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	Methyl (3-Amino-4-fluorophenyl)acetate; 2-(3-Amino-4-fluorophenyl)acetic acid methyl ester; 3-Amino-4-fluorobenzeneacetic acid methyl ester; Methyl 3-amino-4-fluorobenzeneacetate; 4-Fluoro-3-aminophenylacetic acid methyl ester; Methyl α-(3-amino-4-fluorophenyl)acetate; (3-Amino-4-fluorophenyl)acetic acid, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(3-Amino-4-Fluorophenyl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all critical quality attributes are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.