Description

2-[Di(2-Methoxyphenyl)Phosphino]Benzenesulfonic Acid is a specialized organophosphorus ligand with a sulfonic acid functional group, making it a valuable water-soluble catalyst component. This compound is critical for enabling efficient and selective transition metal-catalyzed reactions in aqueous or biphasic systems, offering significant advantages in process sustainability and product isolation. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for applications such as cross-coupling, hydrogenation, and hydroformylation.

Application

• As a water-soluble ligand for rhodium-catalyzed hydroformylation of olefins in aqueous or biphasic media.
• Key component in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for pharmaceutical intermediate synthesis.
• Facilitates asymmetric hydrogenation catalysts for the production of chiral active pharmaceutical ingredients (APIs).
• Used in catalyst recovery and recycling systems due to its solubility properties, improving process economics.
• Employed in academic and industrial research for developing new catalytic methodologies in green chemistry.
• Potential application in specialty polymer synthesis as a functional ligand or monomer.

Basic Information

Product Name	2-[Di(2-Methoxyphenyl)Phosphino]Benzenesulfonic Acid
CAS No.	257290-43-0
Molecular Formula	C21H21O5PS
Molecular Weight	416.42 g/mol
Synonyms	2-(Bis(2-methoxyphenyl)phosphino)benzenesulfonic acid; (2-Sulfophenyl)bis(2-methoxyphenyl)phosphine; 2-[Bis(2-methoxyphenyl)phosphanyl]benzenesulfonic acid; Sulfonated DPP; Water-soluble DPP ligand; DPP-SO3H; 2-(Di-o-anisylphosphino)benzenesulfonic acid; BIS(2-METHOXYPHENYL)(2-SULFOPHENYL)PHOSPHINE
EINECS	Contact for details

Quality Control

Our production of 2-[Di(2-Methoxyphenyl)Phosphino]Benzenesulfonic Acid adheres to strict internal quality standards to ensure batch-to-batch consistency and high purity for catalytic applications. Each lot is fully characterized and undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container must be kept tightly sealed after each use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR	Conforms to structure
31P NMR	Conforms to structure
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.