Description

2-Chloro-N-(4-Fluorobenzyl)Acetamide is a specialized organic compound featuring a chloroacetamide core substituted with a 4-fluorobenzyl group. This molecular architecture makes it a valuable pharmaceutical intermediate and synthetic building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides due to its reactive chloroacetamide moiety.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Synthesis: Employed in organic synthesis for the introduction of the N-(4-fluorobenzyl)acetamide functional group into more complex molecules.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or affinity labels for biochemical and proteomic research.

Basic Information

Product Name	2-Chloro-N-(4-Fluorobenzyl)Acetamide
CAS No.	257279-75-7
Molecular Formula	C9H9ClFNO
Molecular Weight	201.63 g/mol
Synonyms	N-(4-Fluorobenzyl)-2-chloroacetamide; 2-Chloro-N-[(4-fluorophenyl)methyl]acetamide; Acetamide, 2-chloro-N-[(4-fluorophenyl)methyl]-; 2-Chloroacetamide, N-(4-fluorobenzyl)-; 4-Fluorobenzyl Chloroacetamide; N-(4-Fluorobenzyl)chloroacetamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-(4-Fluorobenzyl)Acetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality system supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.