Description

2-Benzothiazoleacetonitrile,α-Fluoro-(9Ci) is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecular entities with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the benzothiazole core and fluorine atom contribute to enhanced efficacy and environmental profile.
• Material Science Precursor: Employed in the synthesis of advanced organic electronic materials, such as fluorophores or charge-transport materials, for OLEDs and sensors.
• Chemical Biology Probe Development: Acts as a versatile scaffold for creating fluorescent tags or activity-based probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Benzothiazoleacetonitrile,α-Fluoro-(9Ci)
CAS No.	256235-36-6
Molecular Formula	C9H5FN2S
Molecular Weight	192.21 g/mol
Synonyms	α-Fluoro-2-benzothiazoleacetonitrile; 2-(Fluoromethyl)benzothiazole-7-carbonitrile; (Fluoromethyl)(2-cyanophenyl)sulfide; 2-(Fluoromethyl)-1,3-benzothiazole-7-carbonitrile; 2-Benzothiazoleacetonitrile, α-fluoro-; 7-Cyano-2-fluoromethylbenzothiazole; 256235-36-6; α-Fluoro-2-benzothiazoleacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Benzothiazoleacetonitrile,α-Fluoro-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the exacting standards required for research and process chemistry. Certificates of Analysis (COA) with complete chromatographic data are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.