Description

Cyclohexanecarboxaldehyde, 3-Fluoro-1-Methyl-, (1R,3S)- (9Ci) is a high-purity, chiral fluorinated aldehyde building block of significant synthetic value. Its defined stereochemistry and reactive aldehyde group make it a critical intermediate for constructing complex molecules in advanced pharmaceutical and agrochemical research. This compound is essential for chemists developing active pharmaceutical ingredients (APIs), chiral ligands, and novel materials where precise spatial orientation and fluorine incorporation are required. CAS No. 256234-81-8.

Application

This chiral fluorinated aldehyde serves as a versatile synthon in sophisticated organic synthesis. Key application areas include:

• Pharmaceutical Intermediate: A key building block for the synthesis of chiral, fluorinated active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom and chiral center can enhance biological activity and environmental stability.
• Chiral Ligand & Catalyst Development: Employed as a precursor for creating novel chiral auxiliaries, ligands for asymmetric catalysis, and organocatalysts.
• Material Science Research: A starting material for synthesizing specialty monomers and polymers with unique optical or electronic properties.
• Fine Chemical Synthesis: Utilized in multi-step syntheses of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	Cyclohexanecarboxaldehyde, 3-Fluoro-1-Methyl-, (1R,3S)- (9Ci)
CAS No.	256234-81-8
Molecular Formula	C8H13FO
Molecular Weight	144.18 g/mol
Synonyms	(1R,3S)-3-Fluoro-1-methylcyclohexanecarboxaldehyde; (1R,3S)-3-Fluoro-1-methyl-1-cyclohexanecarbaldehyde; trans-3-Fluoro-1-methylcyclohexanecarboxaldehyde; 3-Fluoro-1-methylcyclohexanecarbaldehyde (stereoisomer); Fluoromethylcyclohexanecarboxaldehyde; Chiral Fluorinated Cyclohexane Aldehyde; 256234-81-8
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxaldehyde, 3-Fluoro-1-Methyl-, (1R,3S)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC and GC, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at 2-8°C or as specified on the label. Due to its highly volatile and easily oxidized nature, minimize exposure to air, heat, and moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.