Description

(S)-(+)-[(R)-2-Diphenylphosphinoferrocenyl](N,n-Dimethylamino)(2-Diphenylphosphinophenyl)Methane is a highly sophisticated, chiral ferrocenyl phosphine ligand, representing a pinnacle of design in asymmetric catalysis. Its core value lies in enabling exceptionally high enantioselectivity and catalytic activity in a range of transition metal-catalyzed transformations, crucial for producing single-enantiomer intermediates. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance ligands for complex synthetic routes.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, critical for synthesizing chiral pharmaceutical building blocks.
• Asymmetric C-C Bond Formation: Facilitates key reactions such as cross-coupling, allylic substitution, and hydroformylation with high stereocontrol.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs) where precise chirality is required for efficacy and safety.
• Agrochemical Product Development: Enables the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Advanced Material Research: Serves as a precursor or catalyst in the synthesis of chiral polymers and functional materials.
• Academic & Industrial Catalyst Screening: A valuable tool for discovering and optimizing new catalytic processes in both university and corporate R&D laboratories.

Basic Information

Item	Detail
Product Name	(S)-(+)-[(R)-2-Diphenylphosphinoferrocenyl](N,n-Dimethylamino)(2-Diphenylphosphinophenyl)Methane
CAS No.	255884-98-1
Molecular Formula	C47H43FeNP2
Molecular Weight	739.65 g/mol
Synonyms	(S,R)-JOSIPHOS; (S)-(+)-[(R)-2-Diphenylphosphinoferrocenyl](N,N-Dimethylamino)(2-diphenylphosphinophenyl)methane; (S)-(R)-JOSIPHOS; (S,R)-PPF-PCy2; Josiphos ligand SL-J009-1; (S)-(R)-PPF-PCy2; (1S)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine (common naming variant); Ferrocenyl Josiphos ligand
EINECS	Contact for details

Quality Control

Every batch of our (S)-(+)-[(R)-2-Diphenylphosphinoferrocenyl](N,n-Dimethylamino)(2-Diphenylphosphinophenyl)Methane undergoes rigorous analytical testing to ensure exceptional purity and chiral integrity, meeting the stringent requirements of catalysis research and process chemistry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, enantiomeric excess, and key spectroscopic data. Our quality management system is designed to support cGMP and ISO standards for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is between 2°C and 8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.