Description

5-Bromo-2-[(2-Hydroxybenzyl)Amino]Benzenecarbonitrile is a specialized organic intermediate featuring a benzonitrile core substituted with bromine and a functionalized amino-benzyl alcohol group. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or plant growth regulators with specific modes of action.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis or metal-organic frameworks (MOFs) due to its nitrogen and oxygen donor atoms.
• Fluorescent Probe Development: The aromatic structure and substituents make it a candidate scaffold for creating dyes or molecular sensors.
• Academic & Contract Research: Essential for organic chemistry research in universities and CROs (Contract Research Organizations) exploring new synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals for electronics or performance materials.

Basic Information

Product Name	5-Bromo-2-[(2-Hydroxybenzyl)Amino]Benzenecarbonitrile
CAS No.	255865-20-4
Molecular Formula	C14H11BrN2O
Molecular Weight	303.16 g/mol
Synonyms	5-Bromo-2-[(2-hydroxybenzyl)amino]benzonitrile; 2-Amino-5-bromo-N-(2-hydroxybenzyl)benzonitrile; Benzonitrile, 5-bromo-2-[(2-hydroxybenzyl)amino]-; 255865-20-4; 5-Bromo-2-((2-hydroxybenzyl)amino)benzonitrile; 5-Br-2-HBAB; 2-((2-Hydroxybenzyl)amino)-5-bromobenzonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-[(2-Hydroxybenzyl)Amino]Benzenecarbonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.