Description

Aloc-D-Ala-Phe-Lys(Alloc)-Pab-Pnp CAS NO 253863-34-2 is a specialized, protected peptide building block used in solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and fine chemical suppliers engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential assembly of custom peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of new peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Biochemical Probe Development: Employed in the synthesis of labeled or modified peptides for studying biological mechanisms and enzyme activity.
• Combinatorial Chemistry: A valuable building block in libraries for high-throughput screening to identify bioactive compounds.
• Academic Research: Supports fundamental studies in organic chemistry, medicinal chemistry, and peptide science.

Basic Information

Product Name	Aloc-D-Ala-Phe-Lys(Alloc)-Pab-Pnp
CAS No.	253863-34-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fmoc-Lys(Alloc)-OH Pentafluorophenyl Ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[(allyloxy)carbonyl]-L-lysine Pentafluorophenyl Ester; Aloc-D-Ala-Phe-Lys(Alloc)-Pab-OPfp; Pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-[(allyloxy)carbonyl]-L-lysinate; Fmoc-Lys(Alloc)-OPfp; Nα-Fmoc-Nε-Alloc-L-lysine pentafluorophenyl ester; Fmoc-Lys(Alloc)-OPfp ester; Protected Lysine Pentafluorophenyl Ester Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity (by HPLC), identity (by NMR and MS), and chiral integrity. We adhere to cGMP principles where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive) and should be handled under a dry, inert atmosphere to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.