Description

3-(3-Chloro-4-Methylphenyl)Benzonitrile is a specialized aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both chloro and methyl substituents on the phenyl ring, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the benzonitrile core is a common pharmacophore.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials due to its rigid, planar structure and potential for functionalization.
• Polymer & Resin Modifiers: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, or specific optical properties.
• Organic Synthesis Research: Employed in academic and industrial R&D for cross-coupling reactions, cyanation studies, and as a scaffold for library synthesis in medicinal chemistry.
• Dye & Pigment Intermediate: Acts as a precursor in the manufacture of specialized dyes and pigments for high-performance applications.

Basic Information

Product Name	3-(3-Chloro-4-Methylphenyl)Benzonitrile
CAS No.	253679-13-9
Molecular Formula	C14H10ClN
Molecular Weight	227.69 g/mol
Synonyms	3-(3-Chloro-4-methylphenyl)benzonitrile; [1,1'-Biphenyl]-3-carbonitrile, 3'-chloro-4'-methyl-; 3'-Chloro-4'-methyl-[1,1'-biphenyl]-3-carbonitrile; 3-(3-Chloro-p-tolyl)benzonitrile; 3-(3-Chloro-4-methyl-phenyl)-benzonitrile; Benzonitrile, 3-(3-chloro-4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-4-Methylphenyl)Benzonitrile is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by HPLC, GC, and NMR. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.