Description

Z-D-Trp-Leu-Oh is a synthetic dipeptide derivative featuring a D-tryptophan residue. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, particularly in the development of peptide-based pharmaceuticals and research biochemicals. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide drug discovery, medicinal chemistry, and proteomics studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate peptide-protein interactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop novel therapeutic agents with enhanced biological activity and stability.
• Peptide Library Construction: A crucial component in the solid-phase or solution-phase synthesis of diverse peptide libraries for high-throughput screening.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in chromatographic analysis (HPLC, LC-MS).

Basic Information

Item	Detail
Product Name	Z-D-Trp-Leu-Oh
CAS No.	253595-70-9
Molecular Formula	C27H31N3O5
Molecular Weight	477.56 g/mol
Synonyms	Z-D-Tryptophyl-L-leucine; N-Carbobenzoxy-D-tryptophyl-L-leucine; CBZ-D-Trp-L-Leu-OH; Nα-Cbz-D-tryptophyl-L-leucine; (2S)-2-[[(2R)-2-[[(2-Phenylmethoxy)carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoic acid; Z-D-Trp-L-Leu; Benzyloxycarbonyl-D-tryptophyl-L-leucine
EINECS	Contact for details

Quality Control

Our Z-D-Trp-Leu-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.