Description

2-Bromo-1-(2,2-Diethoxyethoxy)-4-Fluorobenzene is a specialized fluorinated and brominated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both halogen substituents and a protected acetal moiety, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated liquid crystals, organic semiconductors, and other advanced functional materials.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.
• Academic & R&D: Utilized in university and institutional laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	2-Bromo-1-(2,2-Diethoxyethoxy)-4-Fluorobenzene
CAS No.	253429-18-4
Molecular Formula	C₁₂H₁₆BrFO₃
Molecular Weight	307.16 g/mol
Synonyms	4-Fluoro-2-bromo-1-(2,2-diethoxyethoxy)benzene; 1-Bromo-2-(2,2-diethoxyethoxy)-5-fluorobenzene; 2-Bromo-1-(2,2-diethoxyethoxy)-4-fluorobenzene; Benzene, 2-bromo-1-(2,2-diethoxyethoxy)-4-fluoro-; [2-Bromo-4-fluorophenoxy]acetaldehyde diethyl acetal
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(2,2-Diethoxyethoxy)-4-Fluorobenzene is produced and tested under strict quality management protocols. We ensure high purity and consistency suitable for demanding research and scale-up applications. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.