Description

3-(3,4-Difluorophenyl)-3-Oxo-Propionic Acid Ethyl Ester is a high-purity fluorinated organic intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, enabling the introduction of the difluorophenyl moiety. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of modern herbicides and fungicides, where the difluorophenyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in organic chemistry research for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the properties and reactivity of organofluorine molecules.

Basic Information

Item	Details
Product Name	3-(3,4-Difluorophenyl)-3-Oxo-Propionic Acid Ethyl Ester
CAS No.	252955-07-0
Molecular Formula	C11H10F2O3
Molecular Weight	228.19 g/mol
Synonyms	Ethyl 3-(3,4-difluorophenyl)-3-oxopropanoate; 3-Oxo-3-(3,4-difluorophenyl)propionic acid ethyl ester; Ethyl 3,4-difluorobenzoylacetate; 3,4-Difluorobenzoylacetic acid ethyl ester; DFBAE; 252955-07-0; Ethyl (3,4-difluorobenzoyl)acetate
EINECS	Contact for details

Quality Control

Our 3-(3,4-Difluorophenyl)-3-Oxo-Propionic Acid Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.