Description

Dimethyl 2-(4-Fluorobenzyl)Malonate is a high-purity fluorinated malonate ester, a versatile and critical building block in advanced organic synthesis. Its value lies in its reactive diester functionality adjacent to a fluorinated benzyl group, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a key intermediate for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems and complex ester backbones.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Organic Synthesis Building Block: Serves in various condensation, alkylation, and cyclization reactions (e.g., Michael additions, Dieckmann condensations) to construct complex heterocycles and carbon chains.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials where fluorinated aromatic units are required.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Item	Details
Product Name	Dimethyl 2-(4-Fluorobenzyl)Malonate
CAS No.	252938-22-0
Molecular Formula	C₁₂H₁₃FO₄
Molecular Weight	240.23 g/mol
Synonyms	Dimethyl (4-Fluorobenzyl)malonate; Propanedioic acid, 2-[(4-fluorophenyl)methyl]-, 1,3-dimethyl ester; 2-(4-Fluorobenzyl)malonic Acid Dimethyl Ester; Malonic acid, (4-fluorobenzyl)-, dimethyl ester; Dimethyl (4-fluorobenzyl)propanedioate
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(4-Fluorobenzyl)Malonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reliable and traceable raw materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.