Description

Potassium 4-Acetylphenyltrifluoroborate is a high-purity organoboron reagent, specifically a potassium aryltrifluoroborate salt, essential for modern synthetic chemistry. This compound serves as a critical coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient and selective formation of carbon-carbon bonds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of complex organic molecules and functionalized intermediates.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-acetyl motifs.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Suzuki-Miyaura Cross-Coupling Reactions: Functions as a stable, air- and moisture-tolerant boronic acid surrogate for palladium-catalyzed couplings with aryl/vinyl halides or triflates.
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules or creating molecular probes for diagnostic applications.
• Catalyst & Ligand Preparation: Serves as a precursor for ligands or catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Potassium 4-Acetylphenyltrifluoroborate
CAS No.	252726-24-2
Molecular Formula	C8H7BF3KO
Molecular Weight	226.05 g/mol
Synonyms	Potassium (4-Acetylphenyl)trifluoroborate; 4-Acetylphenyltrifluoroborate Potassium Salt; Potassium 4-Acetylbenzenetrifluoroborate; (4-Acetylphenyl)trifluoroboronic Acid Potassium Salt; 4-Acetylphenyl-BF3K; 1-(4-(Trifluoroboranyl)phenyl)ethanone Potassium Salt; 4-Acetylphenyl Potassium Trifluoroborate; Potassium Trifluoro(4-acetylphenyl)borate
EINECS	Contact for details

Quality Control

Our Potassium 4-Acetylphenyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C), HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain long-term stability. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.