Description

Z-D-Glu-Tyr-Oh is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of the glutamyl-tyrosine dipeptide. This compound serves as a crucial building block (synthon) in the sophisticated synthesis of complex peptides and peptidomimetics, offering researchers precise control over molecular architecture. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key raw material in the solid-phase and solution-phase synthesis of target peptide sequences for drug discovery programs.
• Biochemical Research: Used as a substrate or inhibitor analog in enzymatic studies, particularly those involving proteases or kinases.
• Peptide Library Construction: An essential component for generating combinatorial peptide libraries to screen for biological activity.
• Neuroscience Research: Potential building block for synthesizing neuropeptides or their analogs for receptor binding studies.
• API Development: Intermediate in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) with peptide backbones.
• Standards & Calibration: Serves as a high-purity reference standard for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	Z-D-Glu-Tyr-Oh
CAS No.	252351-92-1
Molecular Formula	C22H24N2O7
Molecular Weight	428.44 g/mol
Synonyms	N-Benzyloxycarbonyl-D-glutamyl-L-tyrosine; Z-D-Glu-L-Tyr-OH; Z-D-Glutamyl-L-tyrosine; N-Cbz-D-glutamyl-L-tyrosine; Benzyloxycarbonyl-D-glutamyl-L-tyrosine; (2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]pentanedioic acid, N-benzyloxycarbonyl derivative; D-Glutamic acid, N-[(benzyloxy)carbonyl]-, 1-(L-tyrosyl) ester
EINECS	Contact for details

Quality Control

Our Z-D-Glu-Tyr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.