Description

(S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A] is a high-value, chiral organophosphorus compound featuring a unique bicyclic structure. This compound matters as a sophisticated ligand and building block in asymmetric catalysis, enabling the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel chiral catalysts and intermediates.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, including hydrogenation and cross-coupling.
• Key intermediate in the synthesis of novel organocatalysts and phosphine-based ligands.
• Building block for pharmaceutical active ingredients (APIs) requiring high enantiomeric purity.
• Research chemical for developing asymmetric synthetic methodologies in academic and industrial laboratories.
• Precursor in the synthesis of specialty polymers and advanced materials with tailored properties.
• Component in the development of agrochemicals, such as herbicides and fungicides with specific stereochemistry.

Basic Information

Product Name	(S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A]
CAS No.	252288-04-3
Molecular Formula	C8H9O2P
Molecular Weight	168.13 g/mol
Synonyms	(S)-(+)-2,3-Dihydro-1,4-benzodioxaphosphepine; (S)-(+)-4H-1,4-Benzodioxaphosphorin; (S)-(+)-3,5-Dioxa-4-phosphacyclohepta[2,1-a:5,6-a']dinaphthalene (related structure); (S)-1,4-Benzodioxaphosphepine; Chiral Benzodioxaphosphepine; (S)-Benzodioxaphosphole derivative; P-Chiral ligand precursor
EINECS	Contact for details

Quality Control

Our (S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A] is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure high chemical and optical purity. Certificates of Analysis (COA) detailing identity, purity, and specific tests are provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress and oxidation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.