Description

(Val671)-Amyloid Beta/A4 Protein Precursor770 (667-676) CAS NO 252256-43-2 is a synthetic peptide fragment corresponding to a specific sequence of the amyloid precursor protein (APP), a key molecule in Alzheimer's disease research. This high-purity reference standard is critical for advancing scientific understanding of amyloid beta peptide formation and aggregation mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on neurodegenerative diseases and therapeutic target validation.

Application

• Biomedical Research: Used as a critical reference standard in studies investigating the proteolytic processing of APP and the generation of amyloid-beta peptides.
• Drug Discovery & Development: Serves as a key reagent for screening and validating potential therapeutic compounds aimed at modulating APP processing or inhibiting amyloid aggregation.
• Diagnostic Assay Development: Employed in the calibration and validation of immunoassays (ELISA, Western Blot) designed to detect specific APP fragments or related biomarkers.
• Antibody Production & Characterization: Acts as an immunogen or binding target for generating and testing antibodies specific to this region of the APP protein.
• Biochemical & Biophysical Studies: Utilized in structural biology and biophysical analyses to understand peptide conformation, stability, and interaction partners.
• Academic & Institutional Research: Supports fundamental neuroscience research in university and government laboratories worldwide.

Basic Information

Product Name	(Val671)-Amyloid Beta/A4 Protein Precursor770 (667-676)
CAS No.	252256-43-2
Molecular Formula	C55H84N14O13
Molecular Weight	1125.3 g/mol
Synonyms	APP (667-676) Fragment; Amyloid Beta A4 Protein Precursor (667-676); APP770 (667-676); Val671-APP770(667-676); Amyloid Precursor Protein Fragment 667-676; AβPP (667-676); APP Peptide (667-676); KEVMEDHGYL
EINECS	Contact for details

Quality Control

Every batch of (Val671)-Amyloid Beta/A4 Protein Precursor770 (667-676) is manufactured and tested under stringent quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the peptide desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Analysis	Complies with theoretical composition
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.