Description

Ceftobiprole Medocaril Sodium Sterile Powder is a sterile, semi-synthetic, fifth-generation cephalosporin antibiotic prodrug. It is specifically designed for the treatment of serious Gram-positive and Gram-negative bacterial infections, including those caused by methicillin-resistant *Staphylococcus aureus* (MRSA). This high-purity active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers developing advanced injectable antibiotic formulations. It is supplied as a sterile powder to ensure the highest standards of safety and efficacy in final drug products.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of sterile injectable antibiotic formulations.
• Formulation of hospital-acquired pneumonia (HAP) treatments, excluding ventilator-associated pneumonia (VAP).
• Development of antibiotics targeting complicated skin and skin structure infections (cSSSI).
• Research and development of next-generation antibacterial agents against multi-drug resistant (MDR) pathogens.
• Production of clinical trial materials for evaluating new antibacterial therapies.
• Use in pharmaceutical compounding for specialized patient care under strict regulatory oversight.

Basic Information

Product Name	Ceftobiprole Medocaril Sodium Sterile Powder
CAS No.	252188-71-9
Molecular Formula	C26H25N8O8S2Na
Molecular Weight	664.65 g/mol
Synonyms	Ceftobiprole Medocaril Sodium; Ceftobiprole Sodium; BAL5788 Sodium; (6R,7R)-7-[(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetamido]-3-[(E)-(3R)-1-[(3R)-3-[(carbamoyloxy)methyl]pyrrolidin-1-ium-1-yl]-3-oxoprop-1-en-1-yl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; Ceftobiprole Medocaril (Sterile); Zevtera/Zeftera API
EINECS	Contact for details

Quality Control

Our Ceftobiprole Medocaril Sodium Sterile Powder is manufactured under strict cGMP conditions, ensuring it meets the highest pharmacopeial standards for sterile APIs. Every batch is subjected to a comprehensive battery of tests including sterility, bacterial endotoxins, particulate matter, and related substances analysis. A Certificate of Analysis (COA) and sterility assurance documentation are provided with each shipment to guarantee compliance with your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. The product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment. For long-term stability, store under an inert atmosphere if the primary container is repeatedly opened.

Specification

Item	Specification
Appearance	White to off-white sterile powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Sterility Test	Sterile
Bacterial Endotoxins	< 0.10 EU/mg
Particulate Matter	Meets USP <788> requirements
Uniformity of Dosage Units	Meets Ph. Eur./USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.