Description

1,4-Piperidinedicarboxylicacid,4-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-,1-(9H-Fluoren-9-Ylmethyl)Ester(9Ci) is a sophisticated, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic synthesis. It is primarily utilized in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other specialized fine chemicals.

Application

• Pharmaceutical Intermediates: A key protected intermediate in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid derivative for constructing peptide backbones with specific stereochemistry.
• Chemical Biology Probes: Serves as a building block for creating labeled compounds, inhibitors, and molecular probes used in biochemical and pharmacological research.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands, organocatalysts, and metal-organic frameworks (MOFs) for asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke molecules for clients.
• Academic & Industrial R&D: Supports fundamental research in medicinal chemistry, organic synthesis, and material science within university and corporate laboratories.

Basic Information

Product Name	1,4-Piperidinedicarboxylicacid,4-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-,1-(9H-Fluoren-9-Ylmethyl)Ester(9Ci)
CAS No.	252029-00-8
Molecular Formula	C31H30N2O6
Molecular Weight	526.58 g/mol
Synonyms	Fmoc-4-Amino-1,4-piperidinedicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester; 4-[(Fmoc-amino)]-1,4-piperidinedicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester; 1-(9H-Fluoren-9-ylmethyl) 4-({[(9H-fluoren-9-ylmethoxy)carbonyl]amino})piperidine-1,4-dicarboxylate; Fmoc-4-Amino-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester (common mis-assignment check); Protected 4-Aminopiperidine-1,4-dicarboxylic acid derivative; Fmoc-A4c(1-Fm) (abbreviated peptide nomenclature); CAS 252029-00-8
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity (HPLC), chiral purity, and impurity profiles are available upon request. We adhere to cGMP principles for manufacturing critical intermediates, supporting our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.