Description

N,n-Diboc-2-Chloro-4-Aminoaniline is a high-purity, protected aniline derivative of significant importance in advanced organic synthesis. This compound serves as a critical, multi-functional building block for the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and other high-value intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing functionalized aniline cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Peptide Mimetics & Linker Chemistry: The protected amine and aniline functionalities make it valuable for constructing peptide-like structures and bioconjugation linkers.
• Material Science Research: Employed as a monomer or functionalizing agent in the development of advanced polymers and functional materials.
• Dye & Pigment Intermediate: Serves as a building block for synthesizing specialized azo dyes and organic pigments.
• Cross-Coupling Reactions: The halogenated aromatic ring makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).

Basic Information

Product Name	N,n-Diboc-2-Chloro-4-Aminoaniline
CAS No.	252019-51-5
Molecular Formula	C₁₇H₂₅ClN₂O₄
Molecular Weight	356.84 g/mol
Synonyms	1,4-Benzenediamine, 2-chloro-N,N-bis[(1,1-dimethylethoxy)carbonyl]-; 2-Chloro-N,N-bis(tert-butoxycarbonyl)-1,4-benzenediamine; N,N-Bis-Boc-2-chloro-p-phenylenediamine; N,N-Di-Boc-2-chloro-1,4-diaminobenzene; 2-Chloro-N1,N4-bis(tert-butoxycarbonyl)benzene-1,4-diamine; Di-Boc protected 2-chloro-1,4-phenylenediamine; tert-Butyl (4-((tert-butoxycarbonyl)amino)-2-chlorophenyl)carbamate
EINECS	Contact for details

Quality Control

Our N,n-Diboc-2-Chloro-4-Aminoaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.