Description

tert-Butyl (1R*,4R*)-4-Acetamidocyclohexylcarbamate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the synthesis of novel therapeutic agents, agrochemicals, and other fine chemicals requiring stereochemical precision.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in areas targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Peptide Mimetics & Conjugate Chemistry: Serves as a protected amino acid derivative for constructing peptide analogs and drug conjugates with improved stability and bioavailability.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and screening of new asymmetric catalytic systems.
• Custom Synthesis & Process Development: Utilized by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up process optimization.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	tert-Butyl (1R*,4R*)-4-Acetamidocyclohexylcarbamate
CAS No.	251947-21-4
Molecular Formula	C13H24N2O3
Molecular Weight	256.34 g/mol
Synonyms	N-[(1R*,4R*)-4-[[(tert-Butoxy)carbonyl]amino]cyclohexyl]acetamide; 4-Acetamidocyclohexylcarbamic Acid tert-Butyl Ester; (1R,4R)-4-(tert-Butoxycarbonylamino)cyclohexylacetamide; Boc-4-Acetamidocyclohexylamine; tert-Butyl N-[(1R,4R)-4-acetamidocyclohexyl]carbamate; (1R,4R)-4-Acetamidocyclohexyl Carbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (1R*,4R*)-4-Acetamidocyclohexylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.