Description

2-Methyl-3-(trifluoromethyl)benzamide is a high-purity, specialized benzamide derivative distinguished by its trifluoromethyl and methyl substituents. This compound is a critical pharmaceutical intermediate and organic building block valued for its ability to modulate the physicochemical properties of target molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research due to its amide functionality and aromatic structure.
• Material Science Research: Intermediate in the synthesis of specialty polymers and liquid crystals where fluorine substitution is desired for specific material properties.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom chemical synthesis services catering to diverse industrial R&D needs.

Basic Information

Product Name	2-Methyl-3-(trifluoromethyl)benzamide
CAS No.	251651-26-0
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	2-Methyl-3-(trifluoromethyl)benzoic acid amide; 3-(Trifluoromethyl)-2-methylbenzamide; 2-Methyl-alpha,alpha,α-trifluoro-m-toluamide; o-Methyl-alpha,alpha,α-trifluoro-m-toluamide; Benzamide, 2-methyl-3-(trifluoromethyl)-; 251651-26-0; Amide of 2-methyl-3-(trifluoromethyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(trifluoromethyl)benzamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.