Description

Fmoc-Dap(Adpoc)-Oh CAS NO 251316-97-9 is a specialized, orthogonally protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise control over side-chain reactivity during the construction of complex peptides and peptidomimetics. It is primarily utilized in pharmaceutical R&D for the development of novel therapeutic agents, including peptide-based drugs and diagnostic tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for introducing the diaminopropionic acid (Dap) residue with orthogonal protecting groups (Fmoc and Adpoc) for complex peptide assembly.
• Pharmaceutical Research & Development: For the synthesis of peptide-based drug candidates, including antimicrobial peptides, hormone analogs, and targeted therapeutics.
• Peptidomimetic Design: Used in creating modified peptide structures with enhanced stability, bioavailability, or specific biological activity.
• Combinatorial Chemistry Libraries: Serves as a valuable component in generating diverse peptide libraries for high-throughput screening against biological targets.
• Bioconjugation: The reactive carboxyl group allows for conjugation to other molecules, carriers, or surfaces in biotech applications.
• Academic Research: A crucial reagent in university and institutional labs studying peptide chemistry, protein engineering, and chemical biology.

Basic Information

Product Name	Fmoc-Dap(Adpoc)-Oh
CAS No.	251316-97-9
Molecular Formula	C₂₈H₂₈N₂O₆
Molecular Weight	488.53 g/mol
Synonyms	Fmoc-Dap(Adpoc)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[[(1-adamantylmethoxy)carbonyl]amino]-L-alanine; Fmoc-L-Dap(Adpoc)-OH; Fmoc-3-[(Adpoc)amino]-L-alanine; Nα-Fmoc-Nβ-Adpoc-L-2,3-diaminopropionic Acid; (2S)-3-[[(Adamantan-1-ylmethoxy)carbonyl]amino]-2-[(9H-fluoren-9-ylmethoxy)formamido]propanoic acid; Fmoc-Dap(1-Adaoc)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Dap(Adpoc)-Oh is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.