Description

Fmoc-Lys(Meabz-Boc)-Oh CAS NO 251103-43-2 is a protected amino acid derivative, specifically an orthogonally protected lysine building block featuring Fmoc, Boc, and Meabz protecting groups. This compound is critical for enabling complex, multi-step solid-phase peptide synthesis (SPPS) by providing selective deprotection pathways. It is an essential reagent for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled incorporation of modified lysine residues into peptide chains, particularly in Fmoc-based strategies.
• Pharmaceutical Research & Development: Used in the synthesis of complex peptide drug candidates, including those with branched or dendrimeric structures.
• Bioconjugation & Labeling: The orthogonal protecting groups allow for the selective attachment of fluorophores, biotin, or other functional moieties to the lysine side chain after deprotection.
• Peptide Library Synthesis: Enables the creation of diverse peptide libraries for high-throughput screening in drug discovery and epitope mapping.
• Antibody-Drug Conjugate (ADC) Development: Serves as a precursor for constructing specialized linkers and payload attachment sites in ADC design.
• Chemical Biology Probes: Integral to synthesizing activity-based probes and other tools for studying enzyme function and protein-protein interactions.

Basic Information

Product Name	Fmoc-Lys(Meabz-Boc)-Oh
CAS No.	251103-43-2
Molecular Formula	C34H39N3O7
Molecular Weight	601.70 g/mol
Synonyms	Fmoc-Lys(Mea-Boc)-OH; Nα-Fmoc-Nε-[(4-{[(tert-butoxy)carbonyl]amino}methyl)benzoyl]-L-lysine; Fmoc-Lys(Mea(Boc))-OH; Nα-Fmoc-Nε-(4-{[(tert-butoxycarbonyl)amino]methyl}benzoyl)-L-lysine; Fmoc-Lys(Mea(Boc))-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(4-((((tert-butoxy)carbonyl)amino)methyl)benzamido)hexanoic acid; Fmoc-Lys(Meabz-Boc)-OH; Fmoc-Lys(Mea(Boc))-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Lys(Meabz-Boc)-Oh is manufactured under strict quality management systems to ensure the high purity and consistency required for sensitive synthetic applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.