Description

Acetamide, 2,2,2-Trifluoro-n-1H-Imidazol-2-Yl- is a specialized fluorinated acetamide derivative featuring a trifluoromethyl group and an imidazole moiety. This unique molecular architecture makes it a valuable high-purity building block for advanced synthetic chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and fine chemical manufacturers engaged in medicinal chemistry, fluorochemistry, and the synthesis of heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially those requiring fluorinated imidazole scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science Research: Acts as a precursor for synthesizing specialized fluorinated polymers or ligands for metal-organic frameworks (MOFs) with unique properties.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) studies to explore the impact of fluorination on the potency and selectivity of target molecules.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-1H-Imidazol-2-Yl-
CAS No.	250693-25-5
Molecular Formula	C6H6F3N3O
Molecular Weight	193.13 g/mol
Synonyms	2,2,2-Trifluoro-N-(1H-imidazol-2-yl)acetamide; 2,2,2-Trifluoro-N-2-imidazolylacetamide; 2-(Trifluoroacetamido)imidazole; 1H-Imidazole-2-carboxamide, N-(trifluoroacetyl)-; N-(1H-Imidazol-2-yl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoroacetimidic acid imidazolide; TFIA
EINECS	Contact for details

Quality Control

We supply Acetamide, 2,2,2-Trifluoro-n-1H-Imidazol-2-Yl- in high-purity grades suitable for research and commercial synthesis. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.