Description

Propanenitrile, 2-Hydroxy-3-Phenoxy-, (2S)- (9Ci) is a chiral, optically active nitrile derivative with a phenoxy functional group. This compound serves as a valuable chiral building block and synthetic intermediate in the production of high-value fine chemicals and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where stereochemistry is critical for biological activity.
• Liquid Crystal Materials: A potential precursor for chiral dopants and advanced organic compounds used in liquid crystal displays (LCDs).
• Asymmetric Catalysis Research: Employed as a ligand precursor or a test substrate in the development of new asymmetric catalytic reactions.
• Fine Chemical Production: Serves as a versatile intermediate for the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	Propanenitrile, 2-Hydroxy-3-Phenoxy-, (2S)- (9Ci)
CAS No.	250670-80-5
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	(S)-2-Hydroxy-3-phenoxypropanenitrile; (2S)-2-Hydroxy-3-phenoxypropanenitrile; (S)-3-Phenoxy-2-hydroxypropionitrile; (S)-Glycidyl phenyl ether cyanohydrin; (S)-2-Hydroxy-3-phenoxypropionitrile; (S)-Phenoxyglycidonitrile; (S)-α-Hydroxy-β-phenoxypropionitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized to confirm identity, purity, and enantiomeric excess (e.e.). We adhere to strict in-process controls and final release specifications. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, chiral purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.