Description

Carbamic Acid, (1Alpha,3Alpha,5Alpha)-6-Oxabicyclo[3.1.0]Hex-3-Yl-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique oxabicyclo[3.1.0]hexane scaffold. This compound is of significant value in modern organic synthesis, particularly for constructing complex molecular architectures with precise stereochemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting the central nervous system.
• Organic Synthesis Reagent: Used in stereoselective reactions to introduce the constrained oxabicyclo[3.1.0]hexane moiety into target molecules.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material for scaling up the production of proprietary compounds under GMP conditions.
• Academic Research: Utilized in methodological studies and the exploration of new catalytic cycles or reaction pathways.

Basic Information

Product Name	Carbamic Acid, (1Alpha,3Alpha,5Alpha)-6-Oxabicyclo[3.1.0]Hex-3-Yl-, 1,1-Dimethylethyl Ester
CAS No.	250659-32-6
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	tert-Butyl (1R,3R,5S)-6-oxabicyclo[3.1.0]hexan-3-ylcarbamate; (1R,3R,5S)-6-Oxabicyclo[3.1.0]hexan-3-amine, N-BOC-; BOC-6-Oxabicyclo[3.1.0]hexan-3-amine; (1R,3R,5S)-tert-Butyl 6-oxabicyclo[3.1.0]hexan-3-ylcarbamate; N-Boc-6-oxabicyclo[3.1.0]hexan-3-amine; 250659-32-6; tert-Butyl ((1R,3R,5S)-6-oxabicyclo[3.1.0]hexan-3-yl)carbamate
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (1Alpha,3Alpha,5Alpha)-6-Oxabicyclo[3.1.0]Hex-3-Yl-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure high chemical and stereochemical purity suitable for demanding pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.