Description

8-(4-Fluorophenyl)-8-Oxooctanoic Acid is a high-purity, fluorinated keto acid building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a terminal carboxylic acid and a ketone group linked by an alkyl chain to a fluorinated aromatic ring, makes it a versatile intermediate for constructing complex molecules. This compound is particularly valuable for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate fluorinated motifs to modulate the biological activity, metabolic stability, and physicochemical properties of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for introducing fluorophenyl ketone functionalities.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances bioactivity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Polymer Modification: Employed to synthesize specialty monomers or additives for engineering plastics to impart specific thermal or chemical resistance.
• Chemical Research: A valuable building block in academic and industrial R&D for exploring new reactions and creating compound libraries for screening.
• Peptide Mimetics & Bio-conjugation: The carboxylic acid group allows for coupling reactions to create peptide analogs or for linking molecules in bioconjugation chemistry.

Basic Information

Product Name	8-(4-Fluorophenyl)-8-Oxooctanoic Acid
CAS No.	250603-11-3
Molecular Formula	C14H17FO3
Molecular Weight	252.28 g/mol
Synonyms	8-Oxo-8-(4-fluorophenyl)octanoic Acid; 4-Fluorobenzoylheptanoic Acid; 8-(4-Fluorobenzoyl)octanoic Acid; ω-(4-Fluorobenzoyl)heptanoic Acid; 1-Carboxy-7-(4-fluorobenzoyl)heptane; 7-(4-Fluorobenzoyl)heptanoic Acid; FPOA; 250603-11-3
EINECS	Contact for details

Quality Control

Every batch of 8-(4-Fluorophenyl)-8-Oxooctanoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, NMR, and IR spectroscopy is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert gas purging to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.