Description

2-Chloro-n-Methoxy-n-Methylisonicotinamide is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals requiring a tailored isonicotinamide scaffold.

Application

• Pharmaceutical Intermediate: Key synthon in the synthesis of novel drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and insecticides with improved efficacy and selectivity.
• Chemical Biology Probes: Serves as a precursor for labeled compounds and molecular probes used in biochemical assay development.
• Material Science: Potential building block for functionalized polymers and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds at various scales, from laboratory to pilot plant.

Basic Information

Product Name	2-Chloro-n-Methoxy-n-Methylisonicotinamide
CAS No.	250263-39-9
Molecular Formula	C9H11ClN2O2
Molecular Weight	214.65 g/mol
Synonyms	2-Chloro-N-methoxy-N-methylisonicotinamide; 2-Chloro-N-methoxy-N-methylpyridine-4-carboxamide; 4-Pyridinecarboxamide, 2-chloro-N-methoxy-N-methyl-; Isonicotinamide, 2-chloro-N-methoxy-N-methyl-; 2-Chloro-N-methoxy-N-methyl-4-pyridinecarboxamide; 2-Chloro-N-methoxy-N-methyl-4-carbamoylpyridine; 250263-39-9; 2-Chloro-N-methoxy-N-methyl-isonicotinamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-Methoxy-n-Methylisonicotinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.