Description

1-n-Boc-cis-1,4-Cyclohexyldiamine is a high-purity, protected diamine building block of significant importance in advanced organic synthesis. Its core value lies in providing a rigid, chiral scaffold with orthogonal amine protection, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients, chiral ligands, and sophisticated polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of bioactive molecules, including protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where its structural rigidity can enhance target specificity and stability.
• Chiral Ligand & Catalyst Synthesis: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics & Macrocycle Construction: The cis-1,4-cyclohexyl backbone is valuable for designing conformationally restricted peptide analogs and macrocyclic compounds.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for producing specialty polyamides, polyurethanes, and epoxy resins with enhanced thermal and mechanical properties.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new chemical entities and material science applications.

Basic Information

Product Name	1-n-Boc-cis-1,4-Cyclohexyldiamine
CAS No.	247570-24-7
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(1R,4S)-4-[(tert-Butoxycarbonyl)amino]cyclohexanamine; cis-4-(Boc-amino)cyclohexylamine; (1R,4S)-4-(Boc-amino)cyclohexan-1-amine; cis-1,4-Cyclohexanediamine, N1-Boc derivative; 1,4-cis-Boc-cyclohexyldiamine; (1S,4R)-4-Aminocyclohexylcarbamic acid tert-butyl ester; tert-Butyl ((1R,4S)-4-aminocyclohexyl)carbamate; BOC-cis-1,4-DACH
EINECS	Contact for details

Quality Control

Our 1-n-Boc-cis-1,4-Cyclohexyldiamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee consistent quality, identity, and purity for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.