Description

2,3,6-Trifluorophenylboronic Acid CAS NO 247564-71-2 is a high-value organoboron building block essential for modern synthetic chemistry. Its trifluorinated phenyl ring and boronic acid functional group make it a critical reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-couplings for synthesizing drug candidates, especially those requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used to construct fluorinated active ingredients for herbicides, fungicides, and pesticides, where fluorine atoms enhance biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or building block for developing novel fluorinated polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs).
• Chemical Biology & Diagnostics: Employed in the synthesis of fluorinated probes, tags, and molecular scaffolds for imaging and diagnostic applications.
• Catalyst & Ligand Development: Used to prepare sophisticated, fluorinated ligands for transition metal catalysis, enabling new reaction pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	2,3,6-Trifluorophenylboronic Acid
CAS No.	247564-71-2
Molecular Formula	C6H4BF3O2
Molecular Weight	175.90 g/mol
Synonyms	(2,3,6-Trifluorophenyl)boronic acid; 2,3,6-Trifluorobenzeneboronic acid; B-(2,3,6-Trifluorophenyl)boronic acid; 2,3,6-Trifluorophenyl-Boronic Acid; Boronic acid, B-(2,3,6-trifluorophenyl)-; 247564-71-2; 2,3,6-Trifluorophenylboronic acid pinacol ester (precursor)
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.