Description

3-Fluoro-4-(Trifluoromethyl)Phenylacetonitril is a high-value fluorinated aromatic nitrile building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of bioactive molecules, including kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides where the fluorine motif enhances biological activity.
• Material Science Research: Used in the development of specialty polymers and liquid crystals with tailored electronic properties.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and emissive layer components.
• Fluorinated Liquid Crystal Development: A critical intermediate for creating stable, high-performance fluorinated mesogens.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination to construct complex biaryl systems.

Basic Information

Product Name	3-Fluoro-4-(Trifluoromethyl)Phenylacetonitril
CAS No.	247113-90-2
Molecular Formula	C9H5F4N
Molecular Weight	203.14 g/mol
Synonyms	2-[3-Fluoro-4-(trifluoromethyl)phenyl]acetonitrile; (3-Fluoro-4-trifluoromethylphenyl)acetonitrile; 4-(Trifluoromethyl)-3-fluorophenylacetonitrile; 3-Fluoro-α-(trifluoromethyl)benzeneacetonitrile; 2-(3-Fluoro-4-(trifluoromethyl)phenyl)ethanenitrile; 3-Fluoro-4-trifluoromethylbenzyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-(Trifluoromethyl)Phenylacetonitril is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.