Description

Abaloparatide is a synthetic 34-amino acid peptide analog of human parathyroid hormone-related protein (PTHrP). It functions as a selective activator of the parathyroid hormone 1 receptor (PTH1R), exhibiting potent anabolic effects on bone tissue. This makes it a critical active pharmaceutical ingredient (API) for the development of osteoporosis treatments. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions in the biotechnology and life sciences sectors.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for the treatment of postmenopausal osteoporosis.
• Clinical Research: Serves as a reference standard and investigational material in clinical trials for bone-related metabolic disorders.
• Drug Development: Used in preclinical and formulation studies for developing novel anabolic bone therapies.
• Biochemical Research: Employed in molecular biology and endocrinology research to study PTH1R signaling pathways and bone metabolism mechanisms.

Basic Information

Product Name	Abaloparatide
CAS No.	247062-33-5
Molecular Formula	C174H300N56O53
Molecular Weight	3961.6 g/mol
Synonyms	BA 058; BIM 44058; Tymlos (Brand Name); Parathyroid Hormone-Related Protein (1-34) Amide, [Ala26,38,Leu27,28,31,Gln29,Har34]hPTHrP-(1-34)-NH2; hPTHrP (1-34) analog; PTH1R agonist; Abaloparatide acetate
EINECS	Contact for details

Quality Control

Our Abaloparatide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and potency meet stringent pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for HPLC purity, peptide content, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Peptide Content (N)	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	5.0% - 12.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.