Description

2-tert-Butoxy-4-Bromobenzonitrile is a specialized aromatic nitrile derivative featuring both bromo and tert-butoxy substituents. This compound is a high-value pharmaceutical intermediate and organic synthesis building block, prized for its unique molecular framework that enables the construction of complex chemical architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags due to its reactive bromine and nitrile functional groups.
• Custom Organic Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers engaged in custom synthesis projects.

Basic Information

Product Name	2-tert-Butoxy-4-Bromobenzonitrile
CAS No.	246219-39-6
Molecular Formula	C11H12BrNO
Molecular Weight	254.12 g/mol
Synonyms	4-Bromo-2-(tert-butoxy)benzonitrile; 2-(tert-Butoxy)-4-bromobenzonitrile; 4-Bromo-2-tert-butoxybenzonitrile; Benzonitrile, 4-bromo-2-(1,1-dimethylethoxy)-; 2-tert-Butyloxy-4-bromobenzonitrile; 4-Bromo-2-(1,1-dimethylethoxy)benzonitrile; 2-(1,1-Dimethylethoxy)-4-bromobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-tert-Butoxy-4-Bromobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.