Description

5-Fluoro-2,3-Dihydrobenzo[B]Furan is a high-value fluorinated heterocyclic building block, essential for the synthesis of complex organic molecules. Its core value lies in its ability to introduce the 5-fluoro-2,3-dihydrobenzofuran scaffold, a privileged structure in medicinal chemistry known for modulating biological activity and improving metabolic stability. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers producing advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental persistence.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its fused aromatic-oxygen heterocycle structure.
• Fluorine Chemistry & Library Synthesis: An important building block for constructing diverse compound libraries in medicinal and combinatorial chemistry for high-throughput screening.

Basic Information

Product Name	5-Fluoro-2,3-Dihydrobenzo[B]Furan
CAS No.	245762-35-0
Molecular Formula	C8H7FO
Molecular Weight	138.14 g/mol
Synonyms	5-Fluoro-2,3-dihydro-1-benzofuran; 5-Fluorodihydrobenzofuran; 2,3-Dihydro-5-fluorobenzofuran; 5-Fluoro-2,3-dihydrobenzofuran; Benzofuran, 5-fluoro-2,3-dihydro-; 245762-35-0; 5-Fluoro-2,3-dihydro-benzo[b]furan
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2,3-Dihydrobenzo[B]Furan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.