Description

2-Oxabicyclo[2.2.1]Heptane-1-Carbonylfluoride,4,7,7-Trimethyl-3-Oxo-,(1S,4R)-(9Ci) is a high-purity, stereochemically defined bicyclic lactone derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which provides a rigid, functionalized scaffold for constructing complex molecules with precise stereochemical control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, especially those targeting neurological and metabolic diseases.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where specific spatial orientation is crucial for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in transition metal catalysis.
• Natural Product Synthesis: Employed in the total synthesis of complex natural products that contain fused bicyclic or lactone motifs.
• Material Science Monomer: Potential use as a specialty monomer for creating polymers with unique thermal or mechanical properties derived from its rigid backbone.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its reactive carbonyl fluoride group.

Basic Information

Item	Details
Product Name	2-Oxabicyclo[2.2.1]Heptane-1-Carbonylfluoride,4,7,7-Trimethyl-3-Oxo-,(1S,4R)-(9Ci)
CAS No.	245655-48-5
Molecular Formula	C10H13FO3
Molecular Weight	200.21 g/mol
Synonyms	(1S,4R)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl fluoride; (1S,4R)-Camphor-10-sulfonyl fluoride lactone derivative; 3-Oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl fluoride, 4,7,7-trimethyl-, (1S,4R)-; Bicyclo[2.2.1]heptane-1-carbonyl fluoride, 2-oxa-4,7,7-trimethyl-3-oxo-, (1S,4R)-; (1S,4R)-10-Camphorsulfonyl fluoride lactone; (1S,4R)-3-Oxo-4,7,7-trimethyl-2-oxabicyclo[2.2.1]heptane-1-carbonyl fluoride
EINECS	Contact for details

Quality Control

Every batch of our 2-Oxabicyclo[2.2.1]Heptane-1-Carbonylfluoride,4,7,7-Trimethyl-3-Oxo-,(1S,4R)-(9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, critical for your sensitive synthetic applications. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and chiral analysis is supplied with each shipment to guarantee compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1S,4R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.