Description

Hexadecanamide, n-[(1R,2R)-2-(4-Chlorophenyl)-2-Hydroxy-1-(1-Pyrrolidinylmethyl)Ethyl]- is a high-purity, stereochemically defined organic compound of significant interest in advanced chemical synthesis. This molecule matters for its role as a sophisticated chiral building block or intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and specialty chemical companies focused on creating novel therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of complex drug candidates, particularly in central nervous system (CNS) or receptor-targeted therapies.
• Asymmetric Synthesis: Used as a precursor or reagent in catalytic and stoichiometric asymmetric reactions to introduce specific stereocenters.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs within pharmaceutical R&D.
• Reference Standard: Acts as a high-purity analytical standard for method development, validation, and quality control in regulatory filings.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein-ligand interactions.
• Process Chemistry Development: Scaled for use in route scouting and optimization for the commercial manufacturing of APIs.

Basic Information

Product Name	Hexadecanamide, n-[(1R,2R)-2-(4-Chlorophenyl)-2-Hydroxy-1-(1-Pyrrolidinylmethyl)Ethyl]-
CAS No.	245329-88-8
Molecular Formula	C29H49ClN2O2
Molecular Weight	493.17 g/mol
Synonyms	N-[(1R,2R)-2-(4-Chlorophenyl)-2-hydroxy-1-(pyrrolidin-1-ylmethyl)ethyl]hexadecanamide; (1R,2R)-N-[2-(4-Chlorophenyl)-2-hydroxy-1-(pyrrolidin-1-ylmethyl)ethyl]palmitamide; (R,R)-2-Amino-1-(4-chlorophenyl)-1-(pyrrolidin-1-yl)propan-1-ol Palmitamide Derivative; 245329-88-8; UNII-Contact for details; Palmitic acid amide derivative of (1R,2R)-2-Amino-1-(4-chlorophenyl)-1-(pyrrolidin-1-yl)propan-1-ol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) are available upon request, detailing comprehensive specifications. We adhere to cGMP guidelines where applicable to support our clients in pharmaceutical development and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider using an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.