Description

3,4-Pyridinedicarbonitrile, 2-Iodo-6-Phenyl- is a high-value, multi-functional heterocyclic building block characterized by its pyridine core with strategically positioned cyano and iodo substituents. This compound is essential for advanced organic synthesis, particularly in the development of complex molecules for pharmaceutical and agrochemical research. It serves as a critical intermediate for medicinal chemists and process development scientists engaged in cross-coupling reactions, nucleophilic substitutions, and the construction of novel nitrogen-containing scaffolds. The product is supplied under strict quality control to ensure batch-to-batch consistency for demanding R&D and scale-up applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the creation of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodo and cyano groups make it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions.
• Chemical Biology: Serves as a versatile probe or linker in bioconjugation and the development of biochemical tools.
• Academic & Industrial R&D: Fundamental research reagent for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3,4-Pyridinedicarbonitrile, 2-Iodo-6-Phenyl-
CAS No.	245079-25-8
Molecular Formula	C13H6IN3
Molecular Weight	331.11 g/mol
Synonyms	2-Iodo-6-phenyl-3,4-pyridinedicarbonitrile; 2-Iodo-6-phenylpyridine-3,4-dicarbonitrile; 6-Phenyl-2-iodopyridine-3,4-dicarbonitrile; 3,4-Dicyano-2-iodo-6-phenylpyridine; 245079-25-8; AI3-52375; CTK8I7555; ZINC000005259777; AKOS040757623; DB-078006
EINECS	Contact for details

Quality Control

Every batch of 3,4-Pyridinedicarbonitrile, 2-Iodo-6-Phenyl- is manufactured and analyzed under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of research and development applications across pharmaceutical and chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.