Description

(R)-Segphos is a highly valuable chiral diphosphine ligand widely used in asymmetric catalysis. Its significance lies in its ability to induce high enantioselectivity in a variety of transition metal-catalyzed reactions, enabling the production of single-enantiomer compounds critical for advanced research and manufacturing. This product is essential for chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for developing new active ingredients and high-value intermediates.

Application

• Asymmetric hydrogenation of olefins, ketones, and imines for pharmaceutical intermediate synthesis.
• Asymmetric C-C bond-forming reactions, including cross-coupling and allylic alkylation.
• Catalyst component in the synthesis of chiral active pharmaceutical ingredients (APIs).
• Key ligand for rhodium, ruthenium, and iridium complexes in homogeneous catalysis.
• Research and development of novel catalytic processes in academic and industrial laboratories.
• Production of enantiomerically pure flavors, fragrances, and agrochemicals.

Basic Information

Product Name	(R)-Segphos
CAS No.	244261-66-3
Molecular Formula	C34H32O2P2
Molecular Weight	534.56 g/mol
Synonyms	(R)-(-)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl; (R)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-binaphthyl-2,2'-diylbis(diphenylphosphine); (R)-H8-BINAP; (R)-Octahydrobinaphthyl diphenylphosphine; SegPhos; (R)-SegPhos ligand
EINECS	Contact for details

Quality Control

Our (R)-Segphos is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for reproducible catalytic performance. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and identity confirmation. We adhere to relevant industry standards for fine chemical and catalyst ligand manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain efficacy.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.