Description

Boc-L-β-Homomethionine CAS NO 244251-20-5 is a protected, non-proteinogenic amino acid derivative widely used as a critical building block in peptide synthesis and medicinal chemistry research. Its value lies in providing a versatile, orthogonally protected side chain for the controlled introduction of methionine analogs, enabling the study of structure-activity relationships. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors developing novel peptide-based therapeutics and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for incorporating homomethionine analogs into custom peptide sequences.
• Medicinal Chemistry & Drug Discovery: Used in the research and development of novel peptide drugs, enzyme inhibitors, and receptor ligands.
• Bioconjugation & Protein Engineering: Serves as a precursor for site-specific labeling or modification of proteins and peptides.
• Agrochemical Research: Employed in the synthesis of bioactive peptides with potential pesticidal or plant growth-regulating activity.
• Academic & Institutional Research: A fundamental reagent for studying amino acid metabolism, protein folding, and peptide structure-function.
• Combinatorial Chemistry Libraries: Used to create diverse arrays of compounds for high-throughput screening against biological targets.

Basic Information

Product Name	Boc-L-β-Homomethionine
CAS No.	244251-20-5
Molecular Formula	C11H21NO4S
Molecular Weight	263.35 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-4-(methylthio)butanoic acid; Boc-β-homo-L-Met-OH; N-(tert-Butoxycarbonyl)-L-β-homomethionine; Boc-L-β-Homomethionine; tert-Butyloxycarbonyl-L-β-homomethionine; N-Boc-L-β-homomethionine; Boc-β-homo-L-methionine; L-β-Homomethionine, N-Boc derivative
EINECS	Contact for details

Quality Control

Our Boc-L-β-Homomethionine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -18.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.