Description

Betahistine-D3 Dihydrochloride is a deuterated isotopologue of the pharmaceutical agent Betahistine, specifically labeled with three deuterium atoms. This high-purity compound is essential for advanced research and development, particularly in pharmacokinetic and metabolic studies where precise tracing is required. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical chemists working on drug development and bioanalytical method validation.

Application

• As an internal standard in quantitative LC-MS/MS and GC-MS analysis for accurate measurement of Betahistine in biological matrices.
• For conducting deuterium tracing studies to elucidate the metabolic pathways and bioavailability of Betahistine.
• Use in pharmacokinetic (PK) and pharmacodynamic (PD) research to support new drug applications and regulatory submissions.
• In the development and validation of stable isotope dilution assays to ensure high analytical precision and accuracy.
• As a critical reference material in drug metabolism and disposition (DMPK) studies within pharmaceutical development.
• For quality control and method development in analytical chemistry laboratories servicing the pharmaceutical industry.

Basic Information

Product Name	Betahistine-D3 Dihydrochloride
CAS No.	244094-72-2
Molecular Formula	C8H9D3N2·2HCl
Molecular Weight	251.18 g/mol
Synonyms	2-[2-(Methylamino-d3)ethyl]pyridine Dihydrochloride; Betahistine-d3 Dihydrochloride; (2-(2-(Methyl-d3-amino)ethyl)pyridine) Dihydrochloride; Betahistine (methyl-d3) Dihydrochloride; Serc-d3 Dihydrochloride; Deuteron-d3 Betahistine Dihydrochloride; Betahistine Isotopologue D3 HCl Salt
EINECS	Contact for details

Quality Control

Our Betahistine-D3 Dihydrochloride is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for assay, isotopic enrichment, and impurity profiles. We adhere to relevant industry standards for high-purity reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Isotopic Purity (deuterium, D)	≥98 atom % D
Chemical Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.