Description

4-(Trifluoromethylthio)Phenylacetic Acid is a high-value fluorinated aromatic building block characterized by its unique phenylacetic acid core substituted with a trifluoromethylthio group. This structural motif is critical for modulating the lipophilicity, metabolic stability, and overall bioactivity of advanced molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the metabolically stable SCF₃ moiety.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethylthio group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display and lighting technologies.
• Advanced Polymer Modification: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, or specific reactivity.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for exploring new fluorination reactions and catalytic processes.
• Custom Synthesis & Contract Manufacturing: Supplied for the production of bespoke, high-value compounds for specific client projects.

Basic Information

Product Name	4-(Trifluoromethylthio)Phenylacetic Acid
CAS No.	243977-23-3
Molecular Formula	C₉H₇F₃O₂S
Molecular Weight	236.21 g/mol
Synonyms	2-[4-(Trifluoromethylthio)phenyl]acetic Acid; 4-(Trifluoromethylsulfanyl)benzeneacetic Acid; α-(4-(Trifluoromethylthio)phenyl)acetic Acid; p-(Trifluoromethylthio)phenylacetic Acid; (4-((Trifluoromethyl)thio)phenyl)acetic Acid; 243977-23-3; 4-Trifluoromethylthiophenylacetic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-(Trifluoromethylthio)Phenylacetic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA), including purity assay and impurity profile by HPLC, is supplied with each shipment to guarantee consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.