Description

2',3',6'-Trifluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which can dramatically influence the electronic properties, metabolic stability, and bioavailability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in OLED devices.
• Advanced Material Research: Employed in academic and industrial R&D for creating novel fluorinated polymers and specialty chemicals with unique properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct complex biaryl structures.

Basic Information

Product Name	2',3',6'-Trifluoropropiophenone
CAS No.	243666-18-4
Molecular Formula	C9H7F3O
Molecular Weight	188.15 g/mol
Synonyms	1-(2,3,6-Trifluorophenyl)propan-1-one; 2,3,6-Trifluoropropiophenone; Propiophenone, 2',3',6'-trifluoro-; 2,3,6-Trifluoro-1-phenyl-1-propanone; α-Oxobutane, 2,3,6-trifluoro derivative
EINECS	Contact for details

Quality Control

Our 2',3',6'-Trifluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.